Calculate the HOMA1-IR index from fasting glucose and fasting insulin drawn at the same time. The number is not a diagnosis or individual treatment threshold.
HOMA-IR Insulin Resistance Calculator
Calculated HOMA1-IR
A higher value may reflect greater insulin resistance than a lower value in a comparable population. There is no universal diagnostic cutoff or low/high risk band. This number alone does not diagnose insulin resistance, diabetes or PCOS.
Limits
This indirect index assumes a fasting steady state. Insulin assays vary, and insulin treatment, impaired insulin secretion, acute illness or pregnancy can make comparisons especially difficult. HOMA1 and HOMA2 are different models.
What to review next
Compare earlier results only under similar fasting and laboratory conditions. Discuss fasting glucose, A1C, waist size, blood pressure, lipids, medicines and clinical context together. Do not change medication based on this number.
Questions for a visit
- Is this insulin assay and fasting condition comparable with my earlier results?
- How do glucose, A1C and other metabolic results change the interpretation?
- Do I need further testing or follow-up?
Inputs are calculated on this page, not automatically stored or sent to the server. Printed or saved PDFs include the values.
How to use this tool
For fasting glucose 90 mg/dL and insulin 10 μIU/mL from the same draw: 10 × (90/18) ÷ 22.5 = 2.22. Choosing 5.0 mmol/L gives the same value. This example is not a clinical threshold.
Understanding the result
A higher value may reflect greater insulin resistance than a lower value in a comparable population. There is no universal diagnostic cutoff or low/high risk band. This number alone does not diagnose insulin resistance, diabetes or PCOS.
Limits
This indirect index assumes a fasting steady state. Insulin assays vary, and insulin treatment, impaired insulin secretion, acute illness or pregnancy can make comparisons especially difficult. HOMA1 and HOMA2 are different models.
Frequently asked questions
Does a value over 2.5 diagnose insulin resistance?
No. Research cutoffs vary by population, assay and study outcome. This tool does not assign a universal normal or abnormal label.
What if I do not have an insulin result?
HOMA-IR cannot be calculated from glucose alone. Discuss standard tests such as fasting glucose and A1C with a clinician.
Related tools and guides
HbA1c ↔ eAG calculator · Glucose log · Fasting glucose & A1C guide · Health records
Sources
- Matthews et al. 1985
- Wallace et al. 2004
- Insulin assay variation study
- NIDDK: insulin resistance and prediabetes
General health information, not a substitute for medical care. No independent clinician review is claimed. · Sources checked 2026-09-30